Hydroxypropyl methylcellulose (HPMC) is a nonionic cellulose ether made from natural cellulose through alkalization and etherification reactions. The product is a white to off-white powder with excellent thickening, water retention, film-forming and bonding properties. It disperses in cold water and dissolves in hot water, and the solution is transparent.
Main features:
Wide viscosity range (5-200,000mPa·s)
Good pH stability (3-11)
Hot gelation temperature (60-90℃ adjustable)
Excellent film-forming properties
Basic Features
Chemical Nature
Hydroxypropyl methylcellulose (HPMC) is a semi-synthetic high molecular polymer obtained by etherification modification of natural cellulose. Its molecular structure contains both hydroxypropoxy and methoxy functional groups. This unique structure makes it both water-soluble and thermally stable.
Physical parameters
• Appearance: white to off-white flowing powder
• Particle characteristics: 80-120 mesh (180-125μm) screening rate ≥95%
• Bulk density: 0.35-0.45g/cm³ (directly affects packaging and transportation costs)
• True density: 1.39g/cm³ (measured at 25℃)
Solution properties
Special two-stage properties in terms of solubility:
Cold water dispersion stage: Powder rapidly absorbs water and swells
Hot water dissolution stage: Transparent solution is formed above 60°C
Typical solution properties include:
1% solution viscosity range: 5-200,000mPa·s (20°C)
pH stability: Stable in the range of 3-11
Surface tension: 45-55mN/m (1% solution)
Production process
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① Alkalinization treatment: 18% NaOH solution, temperature 35-50℃
② Etherification reaction: CH₃Cl mixed with propylene oxide for etherification
③ Neutralization washing: pH adjusted to 6.5-8.0
④ Drying treatment: fluidized bed drying, moisture ≤5%
⑤ Crushing and grading: obtain target particle size distribution
⑥ Mixing and homogenization: ensure batch consistency
⑦ Finished product packaging: moisture-proof aluminum foil bag packaging
Key points of quality control
Establish a full-process quality monitoring system:
12 testing indicators for raw materials entering the factory
28 key control points in the production process
Technical Parameters
| Low viscosity | 5-50mPa·s | Solution preparation |
| Medium viscosity | 400-600mPa·s | Coating material |
| High viscosity | 5000-200,000mPa·s | Building material application |
Special requirements for pharmaceutical grade
Comply with the latest pharmacopoeia standards:
USP-NF: heavy metals ≤10ppm
EP10.0: microbial limit ≤100cfu/g
JP17: ignition residue ≤1.0%
Food grade certification indicators
Passed international food safety certification:
FCC VII: Arsenic content ≤3mg/kg
EU E464: Sulfur dioxide residue ≤50ppm
Application Areas
Building materials: mortar thickener, water retainer
01
Pharmaceutical preparations: sustained-release matrix, coating materials
02
Food industry: emulsion stabilization, thickener
03
Daily chemical products: shampoo, toothpaste thickening
04
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